These are just a few thoughts ... Hope some of which you haven't had.
Cam angle is only really used to get the car to fire. It will run without it just doesn't know where home is so it tries both possible locations till it fires. So I doubt there is a problem there. Disconnect it and see.
Is the RPM signal erratic on boost? Crank angle may be the cause but if it runs fine low boost I doubt it.
Run high rpm low boost and see if there is still an issue I know it wont make power but you it will isolate whether this is an rpm or a boost problem
Power Supply - Try disconnecting the alternator and running a battery charger while tuning/dyno One thing that is a noise creator that is easily isolated.
Is the timing where it says it is.... Check it with a light .. I have seen crack trigger rings move / or be installed incorrectly by the manufacturer. We check then weld them... As it runs low boost fine probably not the problem but worth a check. A few degrees can make a difference.
Have you checked resistance on the power side of the coils. Had a problem with on a supercharged vy. The ignition power wires run through the plug next to the radiator on passengers side. Was going high with vibration ... replaced the plug with a deutsche and worked perfectly.
The engine isn't moving and stretching/pinching the wiring?
I have heard of issues with the ecu going to low power mode due to high reading above what it expects on certain parameters - grans/sec I think - not sure that would generate a misfire though. HPTuners is down atm so I cant check....
I have been lucky with my high hp stuff and never had those issues.
Let us know what else you try and if it helps... I'll put it in my brains rotation as I usually have my epiphanies at 2am.
I have also just recently had an issue with plug/pins where they would work and then driving - eps right hand corners would disconnect/go high resistance to loose connection. Pulled the plug and removed the suspected faulty wires - crimped the female plugs aa little and Voilą no problems. Hard to trace sometimes.. Mine was easy as it was main GMLAN that was loosing termination at the EBCM.
Hope you get it sorted.
Cheers